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Monoclonal antibody (MAB) therapy for COVID-19

Monoclonal antibody therapy is an option for some COVID-19 patients

Ballad Health continues to benefit from an adequate supply of Emergency Use Authorization (EUA) combination monoclonal antibody (MAB) agents for qualifying patients in our region.

Ballad Health continues to recommend vaccination against coronavirus 2019 (COVID-19) and continued adherence to masking, hand-hygiene and social distancing in efforts to mitigate disease spread.

COVID-19 vaccinations are available at no charge for anyone age 5 or older at Ballad Health. No appointment is necessary, but you can schedule your vaccination online. If you'd like to schedule your vaccination at a Ballad Health clinic or pharmacy, please speak to your provider.

Who is a candidate for monoclonal antibody therapy?

Several criteria, listed below, must all be met to be eligible for monoclonal antibody therapy.

  • Must have COVID-19 symptoms for less than 10 days
  • Adult (18 and older) who meets at least 1 of the following criteria:
    • Body mass index (BMI) ≥35
    • Chronic kidney disease
    • Diabetes
    • Immunosuppressive disease
    • Receiving immunosuppressive treatment
    • Age ≥ 65 years
    • Age ≥ 55 years AND have any of the following:
      • Cardiovascular disease
      • Hypertension
      • Chronic obstructive pulmonary disease (COPD)/other chronic respiratory disease
  • Adolescent (aged 12 to 17 years) who meets at least 1 of the following criteria:
    • Body mass index (BMI) ≥85th percentile for age/gender
    • Sickle cell disease
    • Congenital or acquired heart disease
    • Neurodevelopmental disorders (e.g. cerebral palsy)
    • Medical-related technological dependence (e.g., tracheostomy, gastrostomy or positive pressure ventilation)
    • Asthma, reactive airway or any other chronic respiratory disease that requires daily medication for control
  • Must not have any of the exclusion criteria listed below:
    • Hospitalization
    • Oxygen use or increased use of oxygen due to COVID-19
    • Weight under 40 kg, 88 lbs
  • Must have a positive COVID polymerase chain reaction (PCR) test or antigen

How is monoclonal antibody therapy administered?

MAB can be administered through a 1-hour infusion or through 4 separate 2.5 mL subcutaneous injections. A 1-hour observation is required after either route.

If you test positive for COVID-19 and qualify, please contact your healthcare provider, or schedule a telehealth visit.